Cargando…

Discovery of a Family of Genomic Sequences Which Interact Specifically with the c-MYC Promoter to Regulate c-MYC Expression

G-quadruplex forming sequences are particularly enriched in the promoter regions of eukaryotic genes, especially of oncogenes. One of the most well studied G-quadruplex forming sequences is located in the nuclease hypersensitive element (NHE) III(1) of the c-MYC promoter region. The oncoprotein c-MY...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rezzoug, Francine, Thomas, Shelia D., Rouchka, Eric C., Miller, Donald M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995011/ https://www.ncbi.nlm.nih.gov/pubmed/27551915 http://dx.doi.org/10.1371/journal.pone.0161588

Ejemplares similares

C-myc and N-myc in the developing brain
por: Wey, Alice, et al.
Publicado: (2010)

Gfi1 upregulates c-Myc expression and promotes c-Myc-driven cell proliferation
por: Zhang, Yangyang, et al.
Publicado: (2020)

Alternative c-MYC mRNA Transcripts as an Additional Tool for c-Myc2 and c-MycS Production in BL60 Tumors
por: Ibrahim, Dina, et al.
Publicado: (2022)

Humanized c-Myc Mouse
por: Lehmann, Frank M., et al.
Publicado: (2012)

Targeting c-MYC with T-Cells
por: Helm, Florian, et al.
Publicado: (2013)

Getting to grips with c-Myc
por: Eick, Dirk
Publicado: (2018)

c-myc and N-myc promote active stem cell metabolism and cycling as architects of the developing brain
por: Wey, Alice, et al.
Publicado: (2010)

Cell penetrating thiazole peptides inhibit c-MYC expression via site-specific targeting of c-MYC G-quadruplex
por: Dutta, Debasish, et al.
Publicado: (2018)

PIWIL2 induces c-Myc expression by interacting with NME2 and regulates c-Myc-mediated tumor cell proliferation
por: Yao, Youlin, et al.
Publicado: (2014)

Visualization of ligand-induced c-MYC duplex–quadruplex transition and direct exploration of the altered c-MYC DNA-protein interactions in cells
por: Yuan, Jia-Hao, et al.
Publicado: (2022)

Alterations and Co-Occurrence of C-MYC, N-MYC, and L-MYC Expression are Related to Clinical Outcomes in Various Cancers
por: Lee, Moonjung, et al.
Publicado: (2023)

ACSL4 promotes hepatocellular carcinoma progression via c-Myc stability mediated by ERK/FBW7/c-Myc axis
por: Chen, Junru, et al.
Publicado: (2020)

c-MYC—Making Liver Sick: Role of c-MYC in Hepatic Cell Function, Homeostasis and Disease
por: Zheng, Kang, et al.
Publicado: (2017)

Metastases suppressor NM23-H2 interaction with G-quadruplex DNA within c-MYC promoter nuclease hypersensitive element induces c-MYC expression
por: Thakur, Ram Krishna, et al.
Publicado: (2009)

Do changes in the c-MYC coding sequence contribute to tumorigenesis?
por: Chakraborty, Abhishek A., et al.
Publicado: (2014)

Development of a Smart Fluorescent Probe Specifically Interacting with C-Myc I-Motif
por: Wei, Zuzhuang, et al.
Publicado: (2022)

Exploring the Interaction of New Pyridoquinazoline Derivatives with G-Quadruplex in the c-MYC Promoter Region
por: Princiotto, Salvatore, et al.
Publicado: (2023)

The c-MYC Protooncogene Expression in Cholesteatoma
por: Palkó, Enikő, et al.
Publicado: (2014)

c-Myc steers translation in lymphoma
por: Cargnello, Marie, et al.
Publicado: (2019)

c-MYC and Epithelial Ovarian Cancer
por: Reyes-González, Jeyshka M., et al.
Publicado: (2021)

Zwint facilitates melanoma progression by promoting c-Myc expression
por: Mou, Kuanhou, et al.
Publicado: (2021)

G-Quadruplexes in c-MYC Promoter as Targets for Cancer Therapy
por: Bahls, Bárbara, et al.
Publicado: (2023)

Sequential and Coordinated Actions of c-Myc and N-Myc Control Appendicular Skeletal Development
por: Zhou, Zi-Qiang, et al.
Publicado: (2011)

Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc
por: Madden, Sarah K., et al.
Publicado: (2021)

Transcription profiling of lung adenocarcinomas of c-myc-transgenic mice: Identification of the c-myc regulatory gene network
por: Reymann, Susanne, et al.
Publicado: (2008)

Bax regulates c-Myc-induced mammary tumour apoptosis but not proliferation in MMTV-c-myc transgenic mice
por: Jamerson, M H, et al.
Publicado: (2004)

A Selective Small‐Molecule c‐Myc Degrader Potently Regresses Lethal c‐Myc Overexpressing Tumors
por: Xu, Ying, et al.
Publicado: (2022)

Molecular Analysis of Oncogenes, ras Family Genes (N‐ras, K‐ras, H‐ras), myc Family Genes (c‐myc, N‐myc) and mdm2 in Natural Killer Cell Neoplasms
por: Sugimoto, Kei‐ji, et al.
Publicado: (2002)

SPAG5 upregulation contributes to enhanced c-MYC transcriptional activity via interaction with c-MYC binding protein in triple-negative breast cancer
por: Li, Ming, et al.
Publicado: (2019)

Brief inactivation of c-Myc is not sufficient for sustained regression of c-Myc-induced tumours of pancreatic islets and skin epidermis
por: Pelengaris, Stella, et al.
Publicado: (2004)

Postnatal liver growth and regeneration are independent of c-myc in a mouse model of conditional hepatic c-myc deletion
por: Sanders, Jennifer A, et al.
Publicado: (2012)

Elevated myc expression and c-myc amplification in spontaneously occurring B lymphoid cell lines
Publicado: (1987)

SUMOylation of Myc-Family Proteins
por: Sabò, Arianna, et al.
Publicado: (2014)

CSIG promotes hepatocellular carcinoma proliferation by activating c-MYC expression
por: Cheng, Qian, et al.
Publicado: (2015)

STK33 promotes hepatocellular carcinoma through binding to c-Myc
por: Yang, Tian, et al.
Publicado: (2016)

KPNA2 promotes metabolic reprogramming in glioblastomas by regulation of c-myc
por: Li, Jie, et al.
Publicado: (2018)

Menin enhances c-Myc-mediated transcription to promote cancer progression
por: Wu, Gongwei, et al.
Publicado: (2017)

Alternative DNA structure formation in the mutagenic human c-MYC promoter
por: del Mundo, Imee Marie A., et al.
Publicado: (2017)

Investigating In Situ Expression of c-MYC and Candidate Ubiquitin-Specific Proteases in DLBCL and Assessment for Peptidyl Disruptor Molecule against c-MYC-USP37 Complex
por: Kamran, Durr e Sameen, et al.
Publicado: (2023)

Oncogene addiction to c-MYC in myeloma cells
por: Holien, Toril, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_usqqncfbndf1knjr6id5qkv4l4