Identification of ABC Transporter Interaction of a Novel Cyanoquinoline Radiotracer and Implications for Tumour Imaging by Positron Emission Tomography

BACKGROUND: The epidermal growth factor receptor (EGFR) is overexpressed in many cancers including lung, ovarian, breast, head and neck and brain. Mutation of this receptor has been shown to play a crucial role in the response of non-small cell lung carcinoma (NSCLC) to EGFR-targeted therapies. It i...

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Detalles Bibliográficos
Autores principales: Slade, Rozanna L., Pisaneschi, Federica, Nguyen, Quang-De, Smith, Graham, Carroll, Laurence, Beckley, Alice, Kaliszczak, Maciej A., Aboagye, Eric O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995014/
https://www.ncbi.nlm.nih.gov/pubmed/27552105
http://dx.doi.org/10.1371/journal.pone.0161427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995014/
https://www.ncbi.nlm.nih.gov/pubmed/27552105
http://dx.doi.org/10.1371/journal.pone.0161427

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