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Nox2-derived oxidative stress results in inefficacy of antibiotics against post-influenza S. aureus pneumonia

Clinical post-influenza Staphylococcus aureus pneumonia is characterized by extensive lung inflammation associated with severe morbidity and mortality even after appropriate antibiotic treatment. In this study, we show that antibiotics rescue nicotinamide adenine dinucleotide phosphate (NADPH) oxida...

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Detalles Bibliográficos
Autores principales: Sun, Keer, Yajjala, Vijaya Kumar, Bauer, Christopher, Talmon, Geoffrey A., Fischer, Karl J., Kielian, Tammy, Metzger, Dennis W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995072/
https://www.ncbi.nlm.nih.gov/pubmed/27526712
http://dx.doi.org/10.1084/jem.20150514