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Nox2-derived oxidative stress results in inefficacy of antibiotics against post-influenza S. aureus pneumonia
Clinical post-influenza Staphylococcus aureus pneumonia is characterized by extensive lung inflammation associated with severe morbidity and mortality even after appropriate antibiotic treatment. In this study, we show that antibiotics rescue nicotinamide adenine dinucleotide phosphate (NADPH) oxida...
Autores principales: | Sun, Keer, Yajjala, Vijaya Kumar, Bauer, Christopher, Talmon, Geoffrey A., Fischer, Karl J., Kielian, Tammy, Metzger, Dennis W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995072/ https://www.ncbi.nlm.nih.gov/pubmed/27526712 http://dx.doi.org/10.1084/jem.20150514 |
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