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Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio

Collaboration among the multitude of RNA-binding proteins (RBPs) is ubiquitous, yet our understanding of these key regulatory complexes has been limited to single RBPs. We investigated combinatorial translational regulation by Drosophila Pumilio (Pum) and Nanos (Nos), which control development, fert...

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Detalles Bibliográficos
Autores principales: Weidmann, Chase A, Qiu, Chen, Arvola, René M, Lou, Tzu-Fang, Killingsworth, Jordan, Campbell, Zachary T, Tanaka Hall, Traci M, Goldstrohm, Aaron C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995099/
https://www.ncbi.nlm.nih.gov/pubmed/27482653
http://dx.doi.org/10.7554/eLife.17096