Modulation of T-bet and Eomes during Maturation of Peripheral Blood NK Cells Does Not Depend on Licensing/Educating KIR

Peripheral natural killer (NK) cells upregulate T-bet and downregulate Eomes, the key transcription factors regulating NK cell maturation and function during the last maturation steps toward terminally differentiated effector cells. During this process, NK cells acquire killer immunoglobulin-like re...

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Detalles Bibliográficos
Autores principales: Pradier, Amandine, Simonetta, Federico, Waldvogel, Sophie, Bosshard, Carine, Tiercy, Jean-Marie, Roosnek, Eddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995208/
https://www.ncbi.nlm.nih.gov/pubmed/27605928
http://dx.doi.org/10.3389/fimmu.2016.00299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995208/
https://www.ncbi.nlm.nih.gov/pubmed/27605928
http://dx.doi.org/10.3389/fimmu.2016.00299

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