Neuroprotective Effect of Non-viral Gene Therapy Treatment Based on Tetanus Toxin C-fragment in a Severe Mouse Model of Spinal Muscular Atrophy

Spinal muscular atrophy (SMA) is a hereditary childhood disease that causes paralysis and progressive degeneration of skeletal muscles and spinal motor neurons. SMA is associated with reduced levels of full-length Survival of Motor Neuron (SMN) protein, due to mutations in the Survival of Motor Neur...

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Detalles Bibliográficos
Autores principales: Oliván, Sara, Calvo, Ana C., Rando, Amaya, Herrando-Grabulosa, Mireia, Manzano, Raquel, Zaragoza, Pilar, Tizzano, Eduardo F., Aquilera, Jose, Osta, Rosario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995219/
https://www.ncbi.nlm.nih.gov/pubmed/27605908
http://dx.doi.org/10.3389/fnmol.2016.00076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995219/
https://www.ncbi.nlm.nih.gov/pubmed/27605908
http://dx.doi.org/10.3389/fnmol.2016.00076

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