Individual aggregates of amyloid beta induce temporary calcium influx through the cell membrane of neuronal cells

Local delivery of amyloid beta oligomers from the tip of a nanopipette, controlled over the cell surface, has been used to deliver physiological picomolar oligomer concentrations to primary astrocytes or neurons. Calcium influx was observed when as few as 2000 oligomers were delivered to the cell su...

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Detalles Bibliográficos
Autores principales: Drews, Anna, Flint, Jennie, Shivji, Nadia, Jönsson, Peter, Wirthensohn, David, De Genst, Erwin, Vincke, Cécile, Muyldermans, Serge, Dobson, Chris, Klenerman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995397/
https://www.ncbi.nlm.nih.gov/pubmed/27553885
http://dx.doi.org/10.1038/srep31910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995397/
https://www.ncbi.nlm.nih.gov/pubmed/27553885
http://dx.doi.org/10.1038/srep31910

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