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Individual aggregates of amyloid beta induce temporary calcium influx through the cell membrane of neuronal cells
Local delivery of amyloid beta oligomers from the tip of a nanopipette, controlled over the cell surface, has been used to deliver physiological picomolar oligomer concentrations to primary astrocytes or neurons. Calcium influx was observed when as few as 2000 oligomers were delivered to the cell su...
Autores principales: | Drews, Anna, Flint, Jennie, Shivji, Nadia, Jönsson, Peter, Wirthensohn, David, De Genst, Erwin, Vincke, Cécile, Muyldermans, Serge, Dobson, Chris, Klenerman, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995397/ https://www.ncbi.nlm.nih.gov/pubmed/27553885 http://dx.doi.org/10.1038/srep31910 |
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