Unique quadruple immunofluorescence assay demonstrates mitochondrial respiratory chain dysfunction in osteoblasts of aged and PolgA(−/−) mice

Fragility fractures caused by osteoporosis affect millions of people worldwide every year with significant levels of associated morbidity, mortality and costs to the healthcare economy. The pathogenesis of declining bone mineral density is poorly understood but it is inherently related to increasing...

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Detalles Bibliográficos
Autores principales: Dobson, Philip F., Rocha, Mariana C., Grady, John P., Chrysostomou, Alexia, Hipps, Daniel, Watson, Sharon, Greaves, Laura C., Deehan, David J., Turnbull, Doug M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995399/
https://www.ncbi.nlm.nih.gov/pubmed/27553587
http://dx.doi.org/10.1038/srep31907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995399/
https://www.ncbi.nlm.nih.gov/pubmed/27553587
http://dx.doi.org/10.1038/srep31907

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