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Normalization of human RNA-seq experiments using chimpanzee RNA as a spike-in standard

Normalization of human RNA-seq experiments employing chimpanzee RNA as a spike-in standard is reported. Human and chimpanzee RNAs exhibit single nucleotide variations (SNVs) in average 210-bp intervals. Spike-in chimpanzee RNA would behave the same as the human counterparts during the whole NGS proc...

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Detalles Bibliográficos
Autores principales: Yu, Hannah, Hahn, Yoonsoo, Park, Sang-Ryoul, Chung, Sun-Ku, Jeong, Sangkyun, Yang, Inchul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995400/
https://www.ncbi.nlm.nih.gov/pubmed/27554056
http://dx.doi.org/10.1038/srep31923