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Characterization of HPV16 L1 loop domains in the formation of a type-specific, conformational epitope

BACKGROUND: Virus-like particles (VLPs) formed by the human papillomavirus (HPV) L1 capsid protein are currently being tested in clinical trials as prophylactic vaccines against genital warts and cervical cancer. The efficacy of these vaccines is critically dependent upon L1 type-specific conformati...

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Detalles Bibliográficos
Autores principales: Olcese, Vanessa A, Chen, Yan, Schlegel, Richard, Yuan, Hang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC499545/
https://www.ncbi.nlm.nih.gov/pubmed/15260888
http://dx.doi.org/10.1186/1471-2180-4-29