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Aberrant expression of miR-153 is associated with overexpression of hypoxia-inducible factor-1α in refractory epilepsy

Evidence suggest that overexpression of hypoxia-inducible factor-1α (HIF-1α) is linked to multidrug resistance of epilepsy. Here we explored whether aberrant expression of HIF-1α is regulated by miRNAs. Genome-wide microRNA expression profiling was performed on temporal cortex resected from mesial t...

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Detalles Bibliográficos
Autores principales: Li, Yaohua, Huang, Cheng, Feng, Peimin, Jiang, Yanping, Wang, Wei, Zhou, Dong, Chen, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995460/
https://www.ncbi.nlm.nih.gov/pubmed/27554040
http://dx.doi.org/10.1038/srep32091