Molecular chaperone Hsp27 regulates the Hippo tumor suppressor pathway in cancer

Heat shock protein 27 (Hsp27) is a molecular chaperone highly expressed in aggressive cancers, where it is involved in numerous pro-tumorigenic signaling pathways. Using functional genomics we identified for the first time that Hsp27 regulates the gene signature of transcriptional co-activators YAP...

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Detalles Bibliográficos
Autores principales: Vahid, Sepideh, Thaper, Daksh, Gibson, Kate F., Bishop, Jennifer L., Zoubeidi, Amina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995483/
https://www.ncbi.nlm.nih.gov/pubmed/27555231
http://dx.doi.org/10.1038/srep31842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995483/
https://www.ncbi.nlm.nih.gov/pubmed/27555231
http://dx.doi.org/10.1038/srep31842

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