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Molecular chaperone Hsp27 regulates the Hippo tumor suppressor pathway in cancer
Heat shock protein 27 (Hsp27) is a molecular chaperone highly expressed in aggressive cancers, where it is involved in numerous pro-tumorigenic signaling pathways. Using functional genomics we identified for the first time that Hsp27 regulates the gene signature of transcriptional co-activators YAP...
Autores principales: | Vahid, Sepideh, Thaper, Daksh, Gibson, Kate F., Bishop, Jennifer L., Zoubeidi, Amina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995483/ https://www.ncbi.nlm.nih.gov/pubmed/27555231 http://dx.doi.org/10.1038/srep31842 |
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