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Blockage of Galectin-receptor Interactions by α-lactose Exacerbates Plasmodium berghei-induced Pulmonary Immunopathology

Malaria-associated acute lung injury (ALI) is a frequent complication of severe malaria that is often caused by “excessive” immune responses. To better understand the mechanism of ALI in malaria infection, here we investigated the roles of galectin (Gal)-1, 3, 8, 9 and the receptors of Gal-9 (Tim-3,...

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Detalles Bibliográficos
Autores principales: Liu, Jinfeng, Huang, Shiguang, Su, Xin-zhuan, Song, Jianping, Lu, Fangli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995515/
https://www.ncbi.nlm.nih.gov/pubmed/27554340
http://dx.doi.org/10.1038/srep32024