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Reduced pCREB in Alzheimer's disease prefrontal cortex is reflected in peripheral blood mononuclear cells
Cyclic-AMP response element-binding protein (CREB) signaling has a critical role in the formation of memories. CREB signaling is dysfunctional in the brains of mouse models of Alzheimer's disease (AD), and evidence suggests that CREB signaling may be disrupted in human AD brains as well. Here,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995548/ https://www.ncbi.nlm.nih.gov/pubmed/27480489 http://dx.doi.org/10.1038/mp.2016.111 |