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Interpreting transcriptional changes using causal graphs: new methods and their practical utility on public networks

BACKGROUND: Inference of active regulatory cascades under specific molecular and environmental perturbations is a recurring task in transcriptional data analysis. Commercial tools based on large, manually curated networks of causal relationships offering such functionality have been used in thousand...

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Detalles Bibliográficos
Autores principales: Fakhry, Carl Tony, Choudhary, Parul, Gutteridge, Alex, Sidders, Ben, Chen, Ping, Ziemek, Daniel, Zarringhalam, Kourosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995651/
https://www.ncbi.nlm.nih.gov/pubmed/27553489
http://dx.doi.org/10.1186/s12859-016-1181-8