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Interpreting transcriptional changes using causal graphs: new methods and their practical utility on public networks
BACKGROUND: Inference of active regulatory cascades under specific molecular and environmental perturbations is a recurring task in transcriptional data analysis. Commercial tools based on large, manually curated networks of causal relationships offering such functionality have been used in thousand...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995651/ https://www.ncbi.nlm.nih.gov/pubmed/27553489 http://dx.doi.org/10.1186/s12859-016-1181-8 |