Wnt3a nanodisks promote ex vivo expansion of hematopoietic stem and progenitor cells

BACKGROUND: Wnt proteins modulate development, stem cell fate and cancer through interactions with cell surface receptors. Wnts are cysteine-rich, glycosylated, lipid modified, two domain proteins that are prone to aggregation. The culprit responsible for this behavior is a covalently bound palmitol...

Descripción completa

Detalles Bibliográficos
Autores principales: Lalefar, Nahal R., Witkowski, Andrzej, Simonsen, Jens B., Ryan, Robert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995738/
https://www.ncbi.nlm.nih.gov/pubmed/27553039
http://dx.doi.org/10.1186/s12951-016-0218-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995738/
https://www.ncbi.nlm.nih.gov/pubmed/27553039
http://dx.doi.org/10.1186/s12951-016-0218-5

Ejemplares similares