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Wnt3a nanodisks promote ex vivo expansion of hematopoietic stem and progenitor cells

BACKGROUND: Wnt proteins modulate development, stem cell fate and cancer through interactions with cell surface receptors. Wnts are cysteine-rich, glycosylated, lipid modified, two domain proteins that are prone to aggregation. The culprit responsible for this behavior is a covalently bound palmitol...

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Detalles Bibliográficos
Autores principales:	Lalefar, Nahal R., Witkowski, Andrzej, Simonsen, Jens B., Ryan, Robert O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995738/ https://www.ncbi.nlm.nih.gov/pubmed/27553039 http://dx.doi.org/10.1186/s12951-016-0218-5

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