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Human NOD2 Recognizes Structurally Unique Muramyl Dipeptides from Mycobacterium leprae

The innate immune system recognizes microbial pathogens via pattern recognition receptors. One such receptor, NOD2, via recognition of muramyl dipeptide (MDP), triggers a distinct network of innate immune responses, including the production of interleukin-32 (IL-32), which leads to the differentiati...

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Detalles Bibliográficos
Autores principales: Schenk, Mirjam, Mahapatra, Sebabrata, Le, Phuonganh, Kim, Hee Jin, Choi, Aaron W., Brennan, Patrick J., Belisle, John T., Modlin, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995902/
https://www.ncbi.nlm.nih.gov/pubmed/27297389
http://dx.doi.org/10.1128/IAI.00334-16