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miR-23a/b regulates the balance between osteoblast and adipocyte differentiation in bone marrow mesenchymal stem cells

Age-related osteoporosis is associated with the reduced capacity of bone marrow mesenchymal stem cells (BMSCs) to differentiate into osteoblasts instead of adipocytes. However, the molecular mechanisms that decide the fate of BMSCs remain unclear. In our study, microRNA-23a, and microRNA-23b (miR-23...

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Detalles Bibliográficos
Autores principales: Guo, Qi, Chen, Yusi, Guo, Lijuan, Jiang, Tiejian, Lin, Zhangyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996037/
https://www.ncbi.nlm.nih.gov/pubmed/27606130
http://dx.doi.org/10.1038/boneres.2016.22