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Declining Efficacy of Artemisinin Combination Therapy Against P. Falciparum Malaria on the Thai–Myanmar Border (2003–2013): The Role of Parasite Genetic Factors

Background. Deployment of mefloquine–artesunate (MAS3) on the Thailand–Myanmar border has led to a sustained reduction in falciparum malaria, although antimalarial efficacy has declined substantially in recent years. The role of Plasmodium falciparum K13 mutations (a marker of artemisinin resistance...

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Detalles Bibliográficos
Autores principales: Phyo, Aung Pyae, Ashley, Elizabeth A., Anderson, Tim J. C., Bozdech, Zbynek, Carrara, Verena I., Sriprawat, Kanlaya, Nair, Shalini, White, Marina McDew, Dziekan, Jerzy, Ling, Clare, Proux, Stephane, Konghahong, Kamonchanok, Jeeyapant, Atthanee, Woodrow, Charles J., Imwong, Mallika, McGready, Rose, Lwin, Khin Maung, Day, Nicholas P. J., White, Nicholas J., Nosten, Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996140/
https://www.ncbi.nlm.nih.gov/pubmed/27313266
http://dx.doi.org/10.1093/cid/ciw388