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Imaging Renal Urea Handling in Rats at Millimeter Resolution Using Hyperpolarized Magnetic Resonance Relaxometry

In this study, in vivo T2 heterogeneity of hyperpolarized [(13)C,(15)N(2)]urea in rat kidney has been investigated. Selective quenching of the vascular hyperpolarized (13)C signal with a macromolecular relaxation agent revealed that a long T2 component of the [(13)C,(15)N(2)]urea signal originated f...

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Detalles Bibliográficos
Autores principales: Reed, Galen D., von Morze, Cornelius, Verkman, Alan S., Koelsch, Bertram L., Chaumeil, Myriam M., Lustig, Michael, Ronen, Sabrina M., Bok, Robert A., Sands, Jeff M., Larson, Peder E. Z., Wang, Zhen J., Ardenkjær Larsen, Jan Henrik, Kurhanewicz, John, Vigneron, Daniel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Grapho Publications, LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996281/
https://www.ncbi.nlm.nih.gov/pubmed/27570835
http://dx.doi.org/10.18383/j.tom.2016.00127