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Imaging Renal Urea Handling in Rats at Millimeter Resolution Using Hyperpolarized Magnetic Resonance Relaxometry
In this study, in vivo T2 heterogeneity of hyperpolarized [(13)C,(15)N(2)]urea in rat kidney has been investigated. Selective quenching of the vascular hyperpolarized (13)C signal with a macromolecular relaxation agent revealed that a long T2 component of the [(13)C,(15)N(2)]urea signal originated f...
Autores principales: | Reed, Galen D., von Morze, Cornelius, Verkman, Alan S., Koelsch, Bertram L., Chaumeil, Myriam M., Lustig, Michael, Ronen, Sabrina M., Bok, Robert A., Sands, Jeff M., Larson, Peder E. Z., Wang, Zhen J., Ardenkjær Larsen, Jan Henrik, Kurhanewicz, John, Vigneron, Daniel B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Grapho Publications, LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996281/ https://www.ncbi.nlm.nih.gov/pubmed/27570835 http://dx.doi.org/10.18383/j.tom.2016.00127 |
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