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Contribution of Mesenteric Lymph Nodes and GALT to the Intestinal Foxp3+ Regulatory T-Cell Compartment

BACKGROUND & AIMS: Foxp3+ regulatory T cells (Tregs) in the intestine promote immune tolerance to enteric antigens. Previous studies have shown that C-C chemokine receptor 7 (CCR7)-dependent migration of intestinal dendritic cells to the mesenteric lymph nodes (mLN) is involved in peripheral Fox...

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Detalles Bibliográficos
Autores principales: Geem, Duke, Ngo, Vu, Harusato, Akihito, Chassaing, Benoit, Gewirtz, Andrew T., Newberry, Rodney D., Denning, Timothy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996285/
https://www.ncbi.nlm.nih.gov/pubmed/27570813
http://dx.doi.org/10.1016/j.jcmgh.2015.12.009