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Experimentally‐induced anti‐myeloperoxidase vasculitis does not require properdin, MASP‐2 or bone marrow‐derived C5

Anti‐neutrophil cytoplasmic antibody vasculitis is a systemic autoimmune disease with glomerulonephritis and pulmonary haemorrhage as major clinical manifestations. The name reflects the presence of autoantibodies to myeloperoxidase and proteinase‐3, which bind to both neutrophils and monocytes. Evi...

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Detalles Bibliográficos
Autores principales: Freeley, Simon J, Popat, Reena J, Parmar, Kiran, Kolev, Martin, Hunt, Beverley J, Stover, Cordula M, Schwaeble, Willhelm, Kemper, Claudia, Robson, Michael G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996338/
https://www.ncbi.nlm.nih.gov/pubmed/27235854
http://dx.doi.org/10.1002/path.4754