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Absolute protein quantification of the yeast chaperome under conditions of heat shock

Chaperones are fundamental to regulating the heat shock response, mediating protein recovery from thermal‐induced misfolding and aggregation. Using the QconCAT strategy and selected reaction monitoring (SRM) for absolute protein quantification, we have determined copy per cell values for 49 key chap...

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Detalles Bibliográficos
Autores principales: Mackenzie, Rebecca J., Lawless, Craig, Holman, Stephen W., Lanthaler, Karin, Beynon, Robert J., Grant, Chris M., Hubbard, Simon J., Eyers, Claire E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996341/
https://www.ncbi.nlm.nih.gov/pubmed/27252046
http://dx.doi.org/10.1002/pmic.201500503