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Identification of Copy Number Aberrations in Breast Cancer Subtypes Using Persistence Topology

DNA copy number aberrations (CNAs) are of biological and medical interest because they help identify regulatory mechanisms underlying tumor initiation and evolution. Identification of tumor-driving CNAs (driver CNAs) however remains a challenging task, because they are frequently hidden by CNAs that...

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Detalles Bibliográficos
Autores principales: Arsuaga, Javier, Borrman, Tyler, Cavalcante, Raymond, Gonzalez, Georgina, Park, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996377/
https://www.ncbi.nlm.nih.gov/pubmed/27600228
http://dx.doi.org/10.3390/microarrays4030339