Transcriptome Analysis of Porphyrin-Accumulated and X-Ray-Irradiated Cell Cultures under Limited Proliferation and Non-Lethal Conditions

5-Aminolevulinic acid (ALA) is a precursor of the photosensitizer used in photodynamic therapy. It accumulates in tumor cells and subsequently metabolizes to protoporphyrin IX (PpIX), which generates singlet oxygen after light irradiation. PpIX enhances the generation of reactive oxygen species foll...

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Detalles Bibliográficos
Autores principales: Takahashi, Junko, Misawa, Masaki, Iwahashi, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996386/
https://www.ncbi.nlm.nih.gov/pubmed/27600211
http://dx.doi.org/10.3390/microarrays4010025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996386/
https://www.ncbi.nlm.nih.gov/pubmed/27600211
http://dx.doi.org/10.3390/microarrays4010025

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