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“Upstream Analysis”: An Integrated Promoter-Pathway Analysis Approach to Causal Interpretation of Microarray Data

A strategy is presented that allows a causal analysis of co-expressed genes, which may be subject to common regulatory influences. A state-of-the-art promoter analysis for potential transcription factor (TF) binding sites in combination with a knowledge-based analysis of the upstream pathway that co...

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Detalles Bibliográficos
Autores principales: Koschmann, Jeannette, Bhar, Anirban, Stegmaier, Philip, Kel, Alexander E., Wingender, Edgar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996392/
https://www.ncbi.nlm.nih.gov/pubmed/27600225
http://dx.doi.org/10.3390/microarrays4020270