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Cancer–Osteoblast Interaction Reduces Sost Expression in Osteoblasts and Up-Regulates lncRNA MALAT1 in Prostate Cancer

Dynamic interaction between prostate cancer and the bone microenvironment is a major contributor to metastasis of prostate cancer to bone. In this study, we utilized an in vitro co-culture model of PC3 prostate cancer cells and osteoblasts followed by microarray based gene expression profiling to id...

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Detalles Bibliográficos
Autores principales: Sebastian, Aimy, Hum, Nicholas R., Hudson, Bryan D., Loots, Gabriela G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996404/
https://www.ncbi.nlm.nih.gov/pubmed/27600237
http://dx.doi.org/10.3390/microarrays4040503