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Cancer–Osteoblast Interaction Reduces Sost Expression in Osteoblasts and Up-Regulates lncRNA MALAT1 in Prostate Cancer
Dynamic interaction between prostate cancer and the bone microenvironment is a major contributor to metastasis of prostate cancer to bone. In this study, we utilized an in vitro co-culture model of PC3 prostate cancer cells and osteoblasts followed by microarray based gene expression profiling to id...
Autores principales: | Sebastian, Aimy, Hum, Nicholas R., Hudson, Bryan D., Loots, Gabriela G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996404/ https://www.ncbi.nlm.nih.gov/pubmed/27600237 http://dx.doi.org/10.3390/microarrays4040503 |
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