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Evaluating the Effect of Cell Culture on Gene Expression in Primary Tissue Samples Using Microfluidic-Based Single Cell Transcriptional Analysis

Significant transcriptional heterogeneity is an inherent property of complex tissues such as tumors and healing wounds. Traditional methods of high-throughput analysis rely on pooling gene expression data from hundreds of thousands of cells and reporting a population-wide average that is unable to c...

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Detalles Bibliográficos
Autores principales: Januszyk, Michael, Rennert, Robert C., Sorkin, Michael, Maan, Zeshaan N., Wong, Lisa K., Whittam, Alexander J., Whitmore, Arnetha, Duscher, Dominik, Gurtner, Geoffrey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996408/
https://www.ncbi.nlm.nih.gov/pubmed/27600239
http://dx.doi.org/10.3390/microarrays4040540