Chemical Screens Identify Drugs that Enhance or Mitigate Cellular Responses to Antibody-Toxin Fusion Proteins

The intersection of small molecular weight drugs and antibody-based therapeutics is rarely studied in large scale. Both types of agents are currently part of the cancer armamentarium. However, very little is known about how to combine them in optimal ways. Immunotoxins are antibody-toxin gene fusion...

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Detalles Bibliográficos
Autores principales: Antignani, Antonella, Mathews Griner, Lesley, Guha, Rajarshi, Simon, Nathan, Pasetto, Matteo, Keller, Jonathan, Huang, Manjie, Angelus, Evan, Pastan, Ira, Ferrer, Marc, FitzGerald, David J., Thomas, Craig J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996465/
https://www.ncbi.nlm.nih.gov/pubmed/27556570
http://dx.doi.org/10.1371/journal.pone.0161415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996465/
https://www.ncbi.nlm.nih.gov/pubmed/27556570
http://dx.doi.org/10.1371/journal.pone.0161415

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