Cargando…
Chemical Screens Identify Drugs that Enhance or Mitigate Cellular Responses to Antibody-Toxin Fusion Proteins
The intersection of small molecular weight drugs and antibody-based therapeutics is rarely studied in large scale. Both types of agents are currently part of the cancer armamentarium. However, very little is known about how to combine them in optimal ways. Immunotoxins are antibody-toxin gene fusion...
Autores principales: | Antignani, Antonella, Mathews Griner, Lesley, Guha, Rajarshi, Simon, Nathan, Pasetto, Matteo, Keller, Jonathan, Huang, Manjie, Angelus, Evan, Pastan, Ira, Ferrer, Marc, FitzGerald, David J., Thomas, Craig J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996465/ https://www.ncbi.nlm.nih.gov/pubmed/27556570 http://dx.doi.org/10.1371/journal.pone.0161415 |
Ejemplares similares
-
Immunotoxins: The Role of the Toxin (†)
por: Antignani, Antonella, et al.
Publicado: (2013) -
Targeting Receptors on Cancer Cells with Protein Toxins
por: Antignani, Antonella, et al.
Publicado: (2020) -
Combination Treatments with the PKC Inhibitor, Enzastaurin, Enhance the Cytotoxicity of the Anti-Mesothelin Immunotoxin, SS1P
por: Mattoo, Abid R., et al.
Publicado: (2013) -
Immunogenicity of Immunotoxins Containing Pseudomonas Exotoxin A: Causes, Consequences, and Mitigation
por: Mazor, Ronit, et al.
Publicado: (2020) -
Large-scale pharmacological profiling of 3D tumor models of cancer cells
por: Mathews Griner, Lesley A, et al.
Publicado: (2016)