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The complement factor 5a receptor 1 has a pathogenic role in chronic inflammation and renal fibrosis in a murine model of chronic pyelonephritis

Complement factor 5a (C5a) interaction with its receptor (C5aR1) contributes to the pathogenesis of inflammatory diseases, including acute kidney injury. However, its role in chronic inflammation, particularly in pathogen-associated disorders, is largely unknown. Here we tested whether the developme...

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Detalles Bibliográficos
Autores principales: Choudhry, Naheed, Li, Ke, Zhang, Ting, Wu, Kun-Yi, Song, Yun, Farrar, Conrad A., Wang, Na, Liu, Cheng-Fei, Peng, Qi, Wu, Weiju, Sacks, Steven H., Zhou, Wuding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996631/
https://www.ncbi.nlm.nih.gov/pubmed/27370410
http://dx.doi.org/10.1016/j.kint.2016.04.023