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The complement factor 5a receptor 1 has a pathogenic role in chronic inflammation and renal fibrosis in a murine model of chronic pyelonephritis
Complement factor 5a (C5a) interaction with its receptor (C5aR1) contributes to the pathogenesis of inflammatory diseases, including acute kidney injury. However, its role in chronic inflammation, particularly in pathogen-associated disorders, is largely unknown. Here we tested whether the developme...
Autores principales: | Choudhry, Naheed, Li, Ke, Zhang, Ting, Wu, Kun-Yi, Song, Yun, Farrar, Conrad A., Wang, Na, Liu, Cheng-Fei, Peng, Qi, Wu, Weiju, Sacks, Steven H., Zhou, Wuding |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996631/ https://www.ncbi.nlm.nih.gov/pubmed/27370410 http://dx.doi.org/10.1016/j.kint.2016.04.023 |
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