The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs

Many nonenveloped viruses engage host receptors that initiate capsid conformational changes necessary for genome release. Structural studies on the mechanisms of picornavirus entry have relied on in vitro approaches of virus incubated at high temperatures or with excess receptor molecules to trigger...

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Detalles Bibliográficos
Autores principales: Lee, Hyunwook, Shingler, Kristin L., Organtini, Lindsey J., Ashley, Robert E., Makhov, Alexander M., Conway, James F., Hafenstein, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996645/
https://www.ncbi.nlm.nih.gov/pubmed/27574701
http://dx.doi.org/10.1126/sciadv.1501929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996645/
https://www.ncbi.nlm.nih.gov/pubmed/27574701
http://dx.doi.org/10.1126/sciadv.1501929

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