Cargando…

Oxidative stress in the development, maintenance and resolution of paclitaxel-induced painful neuropathy

Paclitaxel is a first-line chemotherapeutic with the major dose-limiting side effect of painful neuropathy. Previous preclinical studies indicate mitochondrial dysfunction and oxidative stress are associated with this disorder; however no direct assessment of reactive oxygen species (ROS) levels and...

Descripción completa

Detalles Bibliográficos
Autores principales: Duggett, Natalie A., Griffiths, Lisa A., McKenna, Olivia E., de Santis, Vittorio, Yongsanguanchai, Nutcha, Mokori, Esther B., Flatters, Sarah J.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996646/
https://www.ncbi.nlm.nih.gov/pubmed/27393249
http://dx.doi.org/10.1016/j.neuroscience.2016.06.050