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Oxidative stress in the development, maintenance and resolution of paclitaxel-induced painful neuropathy
Paclitaxel is a first-line chemotherapeutic with the major dose-limiting side effect of painful neuropathy. Previous preclinical studies indicate mitochondrial dysfunction and oxidative stress are associated with this disorder; however no direct assessment of reactive oxygen species (ROS) levels and...
Autores principales: | Duggett, Natalie A., Griffiths, Lisa A., McKenna, Olivia E., de Santis, Vittorio, Yongsanguanchai, Nutcha, Mokori, Esther B., Flatters, Sarah J.L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996646/ https://www.ncbi.nlm.nih.gov/pubmed/27393249 http://dx.doi.org/10.1016/j.neuroscience.2016.06.050 |
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