Amino Acids, Independent of Insulin, Attenuate Skeletal Muscle Autophagy in Neonatal Pigs during Endotoxemia

BACKGROUND: Sepsis induces loss of skeletal muscle mass by activating the ubiquitin proteasome (UPS) and autophagy systems. Although muscle protein synthesis in healthy neonatal piglets is responsive to amino acid (AA) stimulation, it is not known if amino acids (AA) can prevent the activation of mu...

Descripción completa

Detalles Bibliográficos
Autores principales: Hernandez-García, Adriana, Manjarín, Rodrigo, Suryawan, Agus, Nguyen, Hanh V., Davis, Teresa A., Orellana, Renán A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996682/
https://www.ncbi.nlm.nih.gov/pubmed/27064245
http://dx.doi.org/10.1038/pr.2016.83

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996682/
https://www.ncbi.nlm.nih.gov/pubmed/27064245
http://dx.doi.org/10.1038/pr.2016.83

Ejemplares similares