Opioid-induced gut microbial disruption and bile dysregulation leads to gut barrier compromise and sustained systemic inflammation

Morphine and its pharmacological derivatives are the most prescribed analgesics for moderate to severe pain management. However, chronic use of morphine reduces pathogen clearance and induces bacterial translocation across the gut barrier. The enteric microbiome has been shown to play a critical rol...

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Detalles Bibliográficos
Autores principales: Banerjee, Santanu, Sindberg, Gregory, Wang, Fuyuan, Meng, Jingjing, Sharma, Umakant, Zhang, Li, Dauer, Patricia, Chen, Chi, Dalluge, Joseph, Johnson, Timothy, Roy, Sabita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996771/
https://www.ncbi.nlm.nih.gov/pubmed/26906406
http://dx.doi.org/10.1038/mi.2016.9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996771/
https://www.ncbi.nlm.nih.gov/pubmed/26906406
http://dx.doi.org/10.1038/mi.2016.9

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