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Angiogenic inhibitors delivered by the type III secretion system of tumor-targeting Salmonella typhimurium safely shrink tumors in mice

Despite of a growing number of bacterial species that apparently exhibit intrinsic tumor-targeting properties, no bacterium is able to inhibit tumor growth completely in the immunocompetent hosts, due to its poor dissemination inside the tumors. Oxygen and inflammatory reaction form two barriers and...

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Detalles Bibliográficos
Autores principales: Shi, Lei, Yu, Bin, Cai, Chun-Hui, Huang, Jian-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996802/
https://www.ncbi.nlm.nih.gov/pubmed/27558018
http://dx.doi.org/10.1186/s13568-016-0226-8