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Shared active site architecture between archaeal PolD and multi-subunit RNA polymerases revealed by X-ray crystallography
Archaeal replicative DNA polymerase D (PolD) constitute an atypical class of DNA polymerases made of a proofreading exonuclease subunit (DP1) and a larger polymerase catalytic subunit (DP2), both with unknown structures. We have determined the crystal structures of Pyrococcus abyssi DP1 and DP2 at 2...
Autores principales: | Sauguet, Ludovic, Raia, Pierre, Henneke, Ghislaine, Delarue, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996933/ https://www.ncbi.nlm.nih.gov/pubmed/27548043 http://dx.doi.org/10.1038/ncomms12227 |
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