Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults

Clonal haematopoiesis is thought to be a rare condition that increases in frequency with age and predisposes individuals to haematological malignancy. Recent studies, utilizing next-generation sequencing (NGS), observed haematopoietic clones in 10% of 70-year olds and rarely in younger individuals....

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Detalles Bibliográficos
Autores principales: Young, Andrew L., Challen, Grant A., Birmann, Brenda M., Druley, Todd E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996934/
https://www.ncbi.nlm.nih.gov/pubmed/27546487
http://dx.doi.org/10.1038/ncomms12484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996934/
https://www.ncbi.nlm.nih.gov/pubmed/27546487
http://dx.doi.org/10.1038/ncomms12484

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