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Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults
Clonal haematopoiesis is thought to be a rare condition that increases in frequency with age and predisposes individuals to haematological malignancy. Recent studies, utilizing next-generation sequencing (NGS), observed haematopoietic clones in 10% of 70-year olds and rarely in younger individuals....
Autores principales: | Young, Andrew L., Challen, Grant A., Birmann, Brenda M., Druley, Todd E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996934/ https://www.ncbi.nlm.nih.gov/pubmed/27546487 http://dx.doi.org/10.1038/ncomms12484 |
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