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Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation

Microtubules function in TGF-β signalling by facilitating the cytoplasmic trafficking of internalized receptors and the nucleocytoplasmic shuttling of Smads. However, nothing is known about whether actin filaments are required for these processes. Here we report that zebrafish actin-bundling protein...

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Detalles Bibliográficos
Autores principales: Liu, Zhaoting, Ning, Guozhu, Xu, Ranran, Cao, Yu, Meng, Anming, Wang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996939/
https://www.ncbi.nlm.nih.gov/pubmed/27545838
http://dx.doi.org/10.1038/ncomms12603