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Protein S-sulfenylation is a fleeting molecular switch that regulates non-enzymatic oxidative folding
The post-translational modification S-sulfenylation functions as a key sensor of oxidative stress. Yet the dynamics of sulfenic acid in proteins remains largely elusive due to its fleeting nature. Here we use single-molecule force-clamp spectroscopy and mass spectrometry to directly capture the reac...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996944/ https://www.ncbi.nlm.nih.gov/pubmed/27546612 http://dx.doi.org/10.1038/ncomms12490 |